[The diffusion and dissolution of metronidazole and doxepin in semisolid pharmaceutical forms through synthetic membranes]. / Estudio de difusión y disolución de metronidazol y doxepina en formas farmacéuticas semisolidas a través de membranas sintéticas.

The dissolution and diffussion methods through homogeneous synthetic membrane were studied in different semisolid topical formulations containing metronidazole and doxepin. The results suggest that the rate of release showed a first order kinetic for one of the formulations and the rate of release described by Higuchi for the others.